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br recurrence in eBC occurs within the first two or
2021-03-03
recurrence in eBC occurs within the first two or three years and then decreases consistently in the interval of three to five years and decreases even more slowly beyond five years. In addition, past survival analysis with longer follow-up suggested that HER2-targeted therapy showed its benefit pr
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br Subsequently the cytotoxicity of BP DACHPt in
2021-03-03
Subsequently, the cytotoxicity of BP/DACHPt in air-exposed water after 72 h was quantified with the MTT assay. As displayed in Fig. 3B and S13, BP/DACHPt is cytotoxic against HeLa ATPγS tetralithium salt in a concentration-dependent manner without NIR laser irradiation. After irradiation, the sur
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br Conflicts of interest br
2021-03-03
Conflicts of interest The authors have no conflict of interest. Acknowledgement The authors would like to thank Dr. David Weaver and Allen Schroering for their technical support. This study was supported by grants from the Moss Foundation and the Hirshberg Foundation for Pancreatic Can
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br Fig Flow cytometry profiles of A cell line after
2021-03-03
Fig. 11. Flow cytometry profiles of A549 cell line after 3 h of incubation with biotin-C6-NLCs and C6-NLCs. Fig. 12. Fluorescence microscopic images of A549 cells after 3 h incubation with biotin-C6-NLCs and C6-NLCs. confirmed efficient cellular uptake of biotin-NLCs. As it can be seen in
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br miR b and miR
2021-03-03
miR-99b and miR-485 Expression Enhances Infective Viral Particle Formation, Viral Release, and In Vitro Cytotoxicity To evaluate the effects of miR-99b and miR-485 on adenoviral repli-cation, PANC-1 and MIA PaCa-2 Bortezomib (PS-341) were infected with AdwtE miR-99b and AdwtE miR-485 at a low v
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br Previous studies have reported that
2021-03-03
Previous studies have reported that most PTEN deletions of primary tumors were concordantly found in metastatic sites [5,6,18]. It is highly possible that PTEN deletions are early occurring mutations as they tend to be observed in multiple lesions. A study on ERG rearrangements and PTEN deletions
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br Despite improvements in cancer screening following the im
2020-08-30
Despite improvements in cancer screening following the im-plementation of the ACA, many patients had no record of having re-ceived cervical or colorectal cancer screening during the study period. These findings suggest that even with increased access to health in-surance coverage many barriers rem
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br ure C IL A GFP
2020-08-30
ure 1C). IL-17A-GFP reporter expression was confined to various lymphoid (Figure 1D) but not epithelial, stromal, or myeloid GastrinI (Figure S1E). IL-1Ra treatment significantly reduced IL-17A-GFP reporter expression by the lymphoid cells (Figures 1D and 1E). Therefore IL-1 signaling is required
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Lindane pesticides Diazinon br Malathion br SISERI database
2020-08-28
Lindane 2005 pesticides Diazinon Malathion SISERI database, (Institut de Radioprotection et de Sûreté Nucléaire, 2015) Annual reports on occupational exposure to ionizing 4152-77-6 in France Exhaustive collection of individual radiation doses received by Ionizing radiation 1996 to 2
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GSK3 br We and others have
2020-08-28
We and others have shown that cases classified as MES subtype have the lowest rates of complete resection and have the poorest prognosis amongst HGSOC [5–8]. In our own cohort we observed that MES sub-type was an independent predictor of overall survival (OS) in HGSOC (34.2 vs. 44.6 months; p =
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MDH examined years of Minnesota state cancer registry data f
2020-08-28
MDH examined 20 years of Minnesota state cancer registry data, from 1988 to 2008, in the two zip codes that encompass the NMCVI study area, using the Minneapolis-St. Paul metropolitan area age-spe-cific cancer rates for comparison. We observed a significant excess of lung cancers among men (398 obse
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br The effect of PEBCA
2020-08-28
The effect of PEBCA-CBZ and free CBZ was also examined in or-thotopically growing MDA-MB-231 tumors without showing the same efficacy as in the MAS98.12 PDX model. Since the influence of these NPs are based on the so-called EPR effect [3], the tumor vasculature is supposed to be a critical factor.
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Gene br Oligonucleotide pull down assay br Pull
2020-08-18
Gene 711 (2019) 143952 2.7. Oligonucleotide pull down assay Pull down assay was performed by extracting nuclear protein from MCF-7 and MDA-MB-231 Anti-Human TNF-alpha, Human Antibody using nuclear extraction kit (Thermo Scientific, USA). 3 μg of biotinylated MMP-9 wild motif, MMP-9 mutant m
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br the PDI values increased implying that
2020-08-18
the PDI values increased, implying that the more complex (e.g. layered) structures appeared in the system [42]. Micellar structures formed by the AA-CUR bioconjugate were not mechanically strong and stiff enough to allow their imaging by scan-ning Amyloid Beta-Peptide 1-40 microscopy. Thus we h
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br BIVA RXc z score analysis br The reference
2020-08-18
BIVA RXc z-score analysis The reference 149-29-1 of Piccoli et al. [24] was used as the chosen reference population for the authors of the Cardoso [34] and Nwosu studies. However, the seven populations described by Toso et al. [18,20] and Malecka-Massalska [21,31,35] [30,32] used control groups